Phototoxic dermatitis

Last Updated: 2023-07-07

Author(s): Anzengruber F., Navarini A.

ICD11: EK2Z

UV-triggered reaction leading to dermatitis but not due to an allergic reaction.

Phototoxic

; photoallergic

 

When a photosensitizer is activated by UV radiation, energy is transferred to the surrounding tissue after it has been absorbed. The cell damage triggered by this is called phototoxic dermatitis. 

A photosensitizer can be plants (e.g. meadow grass dermatitis), perfume (Berloque dermatitis) or systemic drugs (e.g. in PUVA).

In the area of UV-exposed localisations, erythema and possibly also blisters occur. Post-inflammatory hyperpigmentation may occur

.

Anamnesis

Clinic

If necessary, biopsy

UV protection

Elocom cream 1x tgl.

  1. Onoue S, Seto Y, Sato H, Nishida H, Hirota M, Ashikaga T, Api AM, Basketter D, Tokura Y. Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments. J Dermatol Sci. 2017 Jan;85(1):4-11.
  2. Zuba EB, Koronowska S, Osmola-Mańkowska A, Jenerowicz D. Drug-induced Photosensitivity. Acta Dermatovenerol Croat. 2016 Apr;24(1):55-64.

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