Actinic keratoses
Last Updated: 2021-10-18
ICD11: EK90.0
Last Updated: 2021-10-18
Author(s): Anzengruber F., Navarini A.
ICD11: EK90.0
Keratinocytic intraepidermal neoplasia, keratosis solaris, keratosis senilis, keratoma senile, AK, Crasse de Vieillard.
Actinic keratoses (AKs) are now often referred to as in-situ squamous cell carcinomas, actinic precancerous lesions or solar keratoses and arise from the proliferation of atypical epidermal keratinocytes. In the course of time, they can develop into spinocellular carcinomas.
Actinically stressed body regions
Orthokeratosis, dyskeratosis, hyperkeratosis, loss of architecture of the epidermis, solar elastosis and keratocyte atopia.
Apply adequate sun protection, through behaviour (do not stay in the sun between 11:00 and 15:00), textile (UV clothes, hat) and topical (sun cream) protection.
For single lesions:
Photodynamic therapy
1. Conventional PDT:
2. Daylight PDT:
Surgical interventions
Radiotherapy
kV |
Field diameter (cm2) |
Fractionation (cGy) |
Total dose |
Interval between irradiations (days) |
12 |
|
5-7x800 |
4000-5600 |
4-7 |
20 |
<2 |
2-3x800 |
1600-2400 |
4-7 |
|
>2 |
5-7x400 |
2000-2800 |
3-4 |
Chemical peeling
Laser
Avoid common mistakes:
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