Hypomelanosis guttata idiopathica

Last Updated: 2022-07-22

Author(s): Anzengruber F., Navarini A.

ICD11: -

Entity described by

Costa 1951

Cummings 1966

Synonyms

Leucoderma lenticulare disseminatum, idiopathic guttate hypomelanosis

Definition

UV-induced hypopigmentation of the skin.

Epidemiology

Especially in patients with fair skin types and a lot of UV exposure.

Etiopathogenesis

Chronic UV exposure.

Clinical symptoms

Sharply circumscribed, localised mainly on the extensor sides of the extremities, partly confluent, disseminated, whitish macules.

Diagnosis and diagnostic criteria

Anamnesis

Clinical picture

If diagnostic uncertainty exists, a biopsy may be performed.

Typical medical history

UV exposure?

Dermatopathology

Ortho- to hyperkeratosis. Reduced number of melanin granules in the str. basale.

Therapy

No causal therapy.

Use sunscreen to prevent further skin damage.

References

Kakepis M, Havaki S, Katoulis A, Katsambas A, Stavrianeas N, Troupis TG. Idiopathic guttate hypomelanosis: an electron microscopy study. J Eur Acad Dermatol Venereol. 2015 Jul;29(7):1435-8.
Kakepis M, Havaki S, Katoulis A, Katsambas A, Stavrianeas N, Troupis TG. Dermoscopy of idiopathic guttate hypomelanosis. J Dermatol. 2015 Nov;42(11):1118-9.
Juntongjin P, Laosakul K. Idiopathic Guttate Hypomelanosis: A Review of its Etiology, Pathogenesis, Findings, and Treatments. Am J Clin Dermatol. 2016 Aug;17(4):403-11.