Variola vera
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: 1E 70
Last Updated: 2023-07-07
Author(s): Anzengruber F., Navarini A.
ICD11: 1E 70
Variola, true smallpox, smallpox.
Highly contagious, often fatal disease caused by variola verus virus (= Paschen's elementary virus). In 1979, eradication was announced by the WHO. If there is a suspicion of a new outbreak, this must be reported.
Total integument, especially face, extremities, acras. Partly also mucous membranes are affected.
Reticular epidermal degeneration, multichambered intraepidermal pustules, reticulating degeneration of the stratum spinosum, intracellular oedema with the reaction products of poxvirus (Guarnieri bodies).
Pneumonia, bronchitis, encephalomyelitis, toxic myocarditis, nephritis, osteomyelitis.
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